期刊名称：Revista Brasileira de Atividade Física e Saúde
印刷版ISSN：1413-3482
电子版ISSN：2317-1634
出版年度：2014
卷号：19
期号：2
页码：195-195
DOI：10.12820/rbafs.v.19n2p195
出版社：Sociedade Brasileira de Atividade Física & Saúde
摘要：Physical training can be an useful strategy to attenuate the stress markers concentrations and hyperglycemia on type 1 diabetic rats. Thus; the purpose of the present study was to investigate the effects of swimming training on metabolic parameters and stress markers in diabetic and non-diabetic rats. Twenty-four adult male Wistar rats were recruited. The rats were randomly divided into four groups; sedentary control (SC); trained control (TC); sedentary diabetic (SD); and trained diabetic (TD). The diabetic rats received alloxan monohydrate and the trained rats swam for 60 minutes five times per week. The training load was 3.5% and 5% of body weight to diabetic and non-diabetic rats; respectively. After the euthanasia; blood samples for determination of corticosterone; insulin; and glucose levels were collected; and the adrenal weight; adrenal cholesterol concentration; gastrocnemius glycogen concentration; and muscle total protein content were also determined. To compare the groups; a variance analysis was used with Tukey´s post-hoc. The significance level of 5% was adopted. The adrenal weight was higher in SD (17.2±0.6g) than the other groups (SC: 12.2±0.8g; TC: 13.7±0.6g; TD: 14.3±0.8g); and TD had similar values of TC. The corticosterone level of SD was higher than SC and TC. The serum glucose was higher in the diabetic groups and insulin was lower in these groups. Six weeks of swimming training was efficient to reduce stress markers concentration in type 1 rats. Training may be a good tool to avoid the reduction on muscle protein content in type 1 diabetic rats.
