In this article, the adaptive neuro-fuzzy inference system (ANFIS) and multiconfiguration gas-turbines are used to predict the optimal gas-turbine operating parameters. The principle formulations of gas-turbine configurations with various operating conditions are introduced in detail. The effects of different parameters have been analyzed to select the optimum gas-turbine configuration. The adopted ANFIS model has five inputs, namely, isentropic turbine efficiency ( T eff ), isentropic compressor efficiency ( C eff ), ambient temperature ( T 1 ), pressure ratio ( r p ), and turbine inlet temperature (TIT), as well as three outputs, fuel consumption, power output, and thermal efficiency. Both actual reported information, from Baiji Gas-Turbines of Iraq, and simulated data were utilized with the ANFIS model. The results show that, at an isentropic compressor efficiency of 100% and turbine inlet temperature of 1900 K, the peak thermal efficiency amounts to 63% and 375 MW of power resulted, which was the peak value of the power output. Furthermore, at an isentropic compressor efficiency of 100% and a pressure ratio of 30, a peak specific fuel consumption amount of 0.033 kg/kWh was obtained. The predicted results reveal that the proposed model determines the operating conditions that strongly influence the performance of the gas-turbine. In addition, the predicted results of the simulated regenerative gas-turbine (RGT) and ANFIS model were satisfactory compared to that of the foregoing Baiji Gas-Turbines.