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  • 标题:Dietary Total Antioxidant Capacity and Risk of Non-Alcoholic Fatty Liver Disease: A Case‐Control Study
  • 本地全文:下载
  • 作者:Salehi-Sahlabadi, Ammar ; Mokari, Amin ; Elhamkia, Maryam
  • 期刊名称:Journal of Research in Health Sciences
  • 印刷版ISSN:1682-2765
  • 出版年度:2020
  • 卷号:20
  • 期号:3
  • DOI:10.34172/jrhs05395
  • 出版社:Hamadan University of Medical Sciences
  • 摘要:Background : Dietary total antioxidant capacity (DTAC) has been proposed as a tool for assessing the intake of antioxidants. This study aimed to assess whether a relationship exists between dietary total antioxidant capacity (TAC) and the odds of NAFLD. Study design: A case-control study. Methods : In this age‐and sex‐matched case‐control study in 2019, patients with NAFLD and healthy controls were recruited from a hospital clinic. All participants completed a validated 168‐item food frequency questionnaire, the results of which were subsequently used to generate dietary TAC. Oxygen radical absorbance capacity values were used to calculate dietary TAC. Results : Altogether, 225 patients with NAFLD and 450 healthy controls were enrolled. Participants with NAFLD had a higher mean weight, BMI, energy ( P <0.050), and lower physical activity and DTAC scores ( P <0.050) than the control group. In an adjusted model, participants who were in the highest quartile of dietary TAC had a lower risk of NAFLD (odds ratio 0.78, 95% CI: 0.67, 0.91). Conclusion: A high DTAC was related to a decreased risk of NAFLD. Suggest the intake of a diet with high antioxidant capacity is significant at preventing NAFLD. Increasingly itemized investigations in design of randomized control trials require to reveal more insight into these results.
  • 关键词:Non-alcoholic fatty liver disease;Diet;Case-control studies
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