期刊名称：International Journal of Environmental Science and Development
印刷版ISSN：2010-0264
出版年度：2020
卷号：11
期号：9
页码：455-459
DOI：10.18178/ijesd.2020.11.9.1290
摘要：The Molecular Mechanism and Drug Therapy of Heart Failure Yifan Su Heart failure (HF) is a complex clinical syndrome that results from left ventricular myocardial dysfunction and contributes to dyspnea, fatigue and fluid retention. It's essential to characterize disease progression and symptoms to optimize therapy selection. Also, understanding the mechanisms of HF to guide therapy selection is of vital importance. This review focuses on the demonstrating mechanisms of HF and points out the possible pathways involved in the process. Drug therapies of HF with different effects on specific targets are analyzed. Finally, we conclude the features of the now going drugs and depict the future perspectives of drug therapy of HF, including potential new targets and new drug therapies.
关键词：Heart failure (HF); excitation-contraction coupling (E-C coupling); drug therapy
