首页    期刊浏览 2024年11月14日 星期四
登录注册

文章基本信息

  • 标题:Effects of Neurological Disorders on Bone Health
  • 本地全文:下载
  • 作者:Kelly, Ryan R. ; Sidles, Sara J. ; LaRue, Amanda C.
  • 期刊名称:Frontiers in Psychology
  • 电子版ISSN:1664-1078
  • 出版年度:2020
  • 卷号:11
  • 页码:3399-3425
  • DOI:10.3389/fpsyg.2020.612366
  • 出版社:Frontiers Media
  • 摘要:Neurological diseases, particularly in the context of aging, have serious impacts on quality of life and can negatively affect bone health. The brain-bone axis is critically important for skeletal metabolism, sensory innervation, and endocrine cross-talk between these organs. This review discusses current evidence for the cellular and molecular mechanisms by which various neurological disease categories, including autoimmune, developmental, dementia-related, movement, neuromuscular, stroke, trauma, and psychological, impart changes in bone homeostasis and mass, as well as fracture risk. Likewise, how bone may affect neurological function is discussed. Gaining a better understanding of brain-bone interactions, particularly in patients with underlying neurological disorders, may lead to development of novel therapies and discovery of shared risk factors, as well as highlight the need for broad, whole-health clinical approaches toward treatment.
  • 关键词:Neurology; Disease; Osteoporosis; Bone; Mental Health; Depression; PTSD
国家哲学社会科学文献中心版权所有