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  • 标题:Biological Properties of a Citral-Enriched Fraction of Citrus limon Essential Oil
  • 本地全文:下载
  • 作者:Marzia Pucci ; Stefania Raimondo ; Chiara Zichittella
  • 期刊名称:Foods
  • 电子版ISSN:2304-8158
  • 出版年度:2020
  • 卷号:9
  • 期号:9
  • 页码:1290-1305
  • DOI:10.3390/foods9091290
  • 出版社:MDPI Publishing
  • 摘要:Lemon essential oil (LEO) is a well-known flavoring agent with versatile biological activities. In the present study, we have isolated and characterized four citral-enriched fractions of winter LEO. We reported that in murine and human macrophages the pre-treatment with a mix of these fractions (Cfr-LEO) reduces the expression of the pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 induced by LPS. In addition, Cfr-LEO counteracts LPS-induced oxidative stress, as shown by the increase in the GSH/GSSG ratio in comparison to cells treated with LPS alone. Overall, the results reported here encourage the application of EO fractions, enriched in citral, in the nutraceutical industry, not only for its organoleptic properties but also for its protective action against inflammation and oxidative stress.
  • 关键词:Citrus limon (L;) Osbeck; essential oil; citral; nutraceuticals; inflammation; oxidative stress Citrus limon (L;) Osbeck ; essential oil ; citral ; nutraceuticals ; inflammation ; oxidative stress
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