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  • 标题:A Clinical Tool to Predict Low Serum Selenium in Patients with Worsening Heart Failure
  • 本地全文:下载
  • 作者:Ali A. Al-Mubarak ; Niels Grote Beverborg ; Stefan D. Anker
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2020
  • 卷号:12
  • 期号:9
  • 页码:2541-2555
  • DOI:10.3390/nu12092541
  • 出版社:MDPI Publishing
  • 摘要:Selenium is an essential micronutrient, and a low selenium concentration (80% of patients with low selenium (sensitivity of 44%, specificity of 80%). Given that selenium and iron overlap in their physiological roles, we evaluated the shared determinants and prognostic associates. Both deficiencies shared similar clinical characteristics, including the model risk factors and, in addition, a low protein intake and high levels of C-reactive protein. Low selenium was associated with a similar or worse prognosis compared to iron deficiency. In conclusion, although it is difficult to exclude low selenium based on clinical characteristics alone, we provide a prediction tool which identifies heart failure patients at higher risk of having a low selenium status.
  • 关键词:selenium; malnutrition; heart failure; albumin; iron deficiency selenium ; malnutrition ; heart failure ; albumin ; iron deficiency
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