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  • 标题:Resveratrol, Metabolic Syndrome, and Gut Microbiota
  • 本地全文:下载
  • 作者:Alice Chaplin ; Christian Carpéné ; Josep Mercader
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2018
  • 卷号:10
  • 期号:11
  • 页码:1651-1679
  • DOI:10.3390/nu10111651
  • 出版社:MDPI Publishing
  • 摘要:Resveratrol is a polyphenol which has been shown to have beneficial effects on metabolic syndrome-related alterations in experimental animals, including glucose and lipid homeostasis improvement and a reduction in fat mass, blood pressure, low-grade inflammation, and oxidative stress. Clinical trials have been carried out to address its potential; however, results are still inconclusive. Even though resveratrol is partly metabolized by gut microbiota, the relevance of this “forgotten organ” had not been widely considered. However, in the past few years, data has emerged suggesting that the therapeutic potential of this compound may be due to its interaction with gut microbiota, reporting changes in bacterial composition associated with beneficial metabolic outcomes. Even though data is still scarce and for the most part observational, it is promising nevertheless, suggesting that resveratrol supplementation could be a useful tool for the treatment of metabolic syndrome and its associated conditions.
  • 关键词:resveratrol; gut microbiota; metabolic syndrome resveratrol ; gut microbiota ; metabolic syndrome
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