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  • 标题:Vitamin A and Pregnancy: A Narrative Review
  • 本地全文:下载
  • 作者:Sabina Bastos Maia ; Alex Sandro Rolland Souza ; Maria de Fátima Costa Caminha
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2019
  • 卷号:11
  • 期号:3
  • 页码:681-698
  • DOI:10.3390/nu11030681
  • 出版社:MDPI Publishing
  • 摘要:Vitamin A is a crucial micronutrient for pregnant women and their fetuses. In addition to being essential for morphological and functional development and for ocular integrity, vitamin A exerts systemic effects on several fetal organs and on the fetal skeleton. Vitamin A requirements during pregnancy are therefore greater. Vitamin A deficiency (VAD) remains the leading cause of preventable blindness in the world. VAD in pregnant women is a public health issue in most developing countries. In contrast, in some developed countries, excessive vitamin A intake during pregnancy can be a concern since, when in excess, this micronutrient may exert teratogenic effects in the first 60 days following conception. Routine prenatal vitamin A supplementation for the prevention of maternal and infant morbidity and mortality is not recommended; however, in regions where VAD is a public health issue, vitamin A supplementation is recommended to prevent night blindness. Given the importance of this topic and the lack of a complete, up-to-date review on vitamin A and pregnancy, an extensive review of the literature was conducted to identify conflicting or incomplete data on the topic as well as any gaps in existing data.
  • 关键词:Vitamin A; vitamin A deficiency; pregnancy Vitamin A ; vitamin A deficiency ; pregnancy
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