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  • 标题:The Gut Microbiome and the Big Eight
  • 本地全文:下载
  • 作者:Cassandra Suther ; Matthew D. Moore ; Avraham Beigelman
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2020
  • 卷号:12
  • 期号:12
  • 页码:3728-3746
  • DOI:10.3390/nu12123728
  • 出版社:MDPI Publishing
  • 摘要:Food allergies are increasing at an alarming rate, with 6.5% of the general population affected. It has been hypothesized that the increase in allergies stems from the “hygiene hypothesis”. The gut microbiome, a collection of microbiota and their genetic contents from the gastrointestinal tract, has been shown to play a part in the development of food allergies. The Food and Drug Administration requires all regulated food companies to clearly state an inclusion of the major, or “big eight” food allergens on packaging. This review is to provide information on the significant advancements related to the gut microbiome and each of the eight major food allergies individually. Establishment of causal connection between the microbiome and food allergies has uncovered novel mechanisms. New strategies are discussed to prevent future sensitization and reaction through novel treatments involving functional additives and dietary changes that target the microbiome.
  • 关键词:food allergy; microbiome; dysbiosis; short-chain fatty acids; cow milk allergy food allergy ; microbiome ; dysbiosis ; short-chain fatty acids ; cow milk allergy
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