摘要:In this prospective controlled study, we examined 25 adults with adequately controlled (HbA1c level 0.05 vs. r = 0.88, p < 0.05), possibly due to the glycosylation of binding proteins, which affects the affinity constant for 25(OH)D. The elevation of vitamin D levels after the administration of cholecalciferol was comparable in both groups, with slightly higher 25(OH)D3 levels observed in the diabetes group throughout the study since Day 1 (p < 0.05). Overall, our data indicate that in patients with adequately controlled T1DM 25(OH)D3 levels and the therapeutic response to cholecalciferol is similar to that in healthy individuals.
关键词:vitamin D; type 1 diabetes mellitus; cholecalciferol; vitamin D-binding protein vitamin D ; type 1 diabetes mellitus ; cholecalciferol ; vitamin D-binding protein