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  • 标题:Mild synthesis of isoxazoline derivatives via an efficient [4   1] annulation reaction of transient nitrosoalkenes and sulfur ylides
  • 本地全文:下载
  • 作者:Ting-Bi Hua ; Cheng-Xiong Liu ; Wei-Min Hu
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • 期号:1
  • 页码:2078
  • DOI:10.1038/s41598-021-81370-w
  • 出版社:Springer Nature
  • 摘要:Abstract An efficient [4   1] annulation between α -bromooximes and sulfur ylides via in situ generation of nitrosoalkenes under mild basic reaction conditions has been developed, providing an expeditious and scalable approach to synthesize biologically interesting isoxazoline derivatives with good to excellent yields.
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