出版社:Antropološko društvo Srbije i Univerzitet u Nišu, Prirodno-matematički fakultet
摘要:Diversity of nuclear DNA microsatellite markers were analyzed in a reference sample of the population of northeast Bosnia. 437 samples taken from unrelated individuals were processed and three samples of paternity proof were shown. Detection effectiveness profile of the research, points to a valid choice of method of extraction, amplification and genotyping STR loci with PowerPlextm16. Genetic analysis of allelic variants of the 15 STR loci detected 17 samples determined as microvariants. Samples were divided into 15 different allelic variants at 7 different loci, and are: in locus D7S820, D16S539, D3S1358, D18S51, PENTA D, PENTA E and in locus vWA. Genetic analysis of mutations in cases of paternity determined three examples of single-step mutations in the loci FGA, Penta D and D3S1358. Genetic analysis of observed STR loci detected three allelic variant of genotype combination 7/10/11.3 in locus D7S820 Type II.
其他摘要:Diverzitet nuklearnih mikrosatelitnih DNK markera analiziran je u referentnom uzorku stanovništva sjeveroistočne Bosne. Procesirano je 437 uzoraka uzetih od nesrodnih individua i prikazana su tri primjera dokazivanja paterniteta. Uspješnost detekcija prof
关键词:STR;microvariants; mutations;three allelic variant;North-eastern Bosnia
其他关键词:STR;mikrovarijante;mutacija;tri alelna varijanta;sjeveroistočna Bosna