出版社：Korean Society of Environmental Health and Toxicology
摘要：This study is focused on the hepatopreventive effect in cirrhotic rats induced by N,N-dimethylnitrosamine treatment when organic sulfur-containing compounds were orally injected. Biochemical parameters (aspatate transaminase (AST),alanine transaminase (ALT) alkaline phosphatase (ALP),t-protein and t-bilirubin) were measured in serum injured liver tissue. The increased AST and ALT values were significantly reduced by organic sulfur-containing compounds at the oral doses of 50 mg/kg. The result of morphological changes have illustrated the accumulation of liver damages,such as inflammatory cell accumulation and cirrhosis,caused by N,N-dimethylnitrosamine. Also,it was found that liver damages were prevented by the treatment of organic sulfur-containing compounds.
