出版社：Korean Society of Environmental Health and Toxicology
摘要：From the harmfulness expectation test conducted through a toxicity anticipation program,methylcyclohexane turned out to be harmful and simulative,but no carcinogenicity was anticipated. In a four-hour acute inhalation toxicity test,the result showed that lethal concentration (LC50) was 3,750 ppm (15,054 mg/L),which was identified as a harmful substance on the basis of the harmful substance classification standard 2⁄LC50‹20 mg/L)/4 hr (rat) of the Industrial safety and health law. methylcyclohexane fell under the category 4 (2,500⁄ LC50‹5,000 ppm) substance from the GHS standard acute toxicity harmfulness classification. Also,from subchronic inhalation toxicity test that included 6 hours a day,five days a week,and for 13 weeks,we could observe weight,activity,long term weight,blood and blood biochemical influence from the exposure of test substance. No-observed effect level (NOEL) was determined below 100~400 ppm inboth male and female. This material falls under the Category 2 (50~250 ppm/6 hours/90 days) in the GHS (Globally Harmonized System) standard trace long-term whole body toxicity repeated exposure,and can be classified as a harmful substance in accordance with the Industrial Safety and Health Law harmful substance standard NOEL‹0.5 mg/L/ 6 hr/90 day (rat).
