出版社：Korean Society of Environmental Health and Toxicology
摘要：In this study,three different sizes of cerium oxide (CeO2) nanoparticles were synthesized and exposed to Caenorhabditis elegans to investigate the potential harmful effect of CeO2 nanoparticles on the environment. The efects of the CeO2 nanoparticles on C. elegans were assessed at multiple levels. such as with respect to stress response gene expression,growth,reproduction and mortality. Moreover,to test the ecotoxicological relevance of CeOr-induced gene expression. The overall results suggest that CeO2 nanoparticles may provoke ecotoxicity in C. elegans especially with respect to gene expression,reproduction and survival,which can com- prise an important contribution to knowledge on the ecotoxicity of CeO2 nanoparticles. about which lttle data are available. This is particularly valuable in the biomarker research on ecotoxicology,as ecological relevance is a crucial criterion for the applicability of the biomarker in field biomonitoring and ecological risk assess- ment.
关键词：ceria;Caenorhablitis elegans;stress related gene expression
