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  • 标题:Screening Test of Titanium Dioxide N anoparticles
  • 其他标题:티타늄 금속나노입자의 혈액응고작용 검색
  • 本地全文:下载
  • 作者:K wangsik Park
  • 期刊名称:Environmental Health and Toxicology
  • 电子版ISSN:2233-6567
  • 出版年度:2008
  • 卷号:23
  • 期号:4
  • 语种:English
  • 出版社:Korean Society of Environmental Health and Toxicology
  • 摘要:Effects of titanium dioxide nanoparticles on blood coagulation and platelet aggregation were investigated using diluted whole blood and platelet rich plasma (PRP) solution prepared from human and rat blood, respectively. Blood coagulation was monitored by using a whole blood impedance aggregometer and titanium dioxide nanoparticle (10,20,and 40 ppm) did not show any effect on the coagulation both in human and in rat blood. When platelet aggregation was measured by turbidometrice method after addition of titanium dioxide nanoparticles to PRP solution with final concentrations of 1,5 and 10 ppm,no aggregation was observed.
  • 关键词:titanium dioxide nanoparticles;blood coagulation;platelet aggregation
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