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  • 标题:Effects of Silver Nanoparticles Exposed in Somite Stage on Zebrafish Development
  • 其他标题:Somite stage에 노출된 은나노 입자가 zebrafish 발생에 미치는 영향
  • 本地全文:下载
  • 作者:Suk ho Hong ; Hyung Gwi Song ; Kyeong-jun Jeong
  • 期刊名称:Environmental Health and Toxicology
  • 电子版ISSN:2233-6567
  • 出版年度:2009
  • 卷号:24
  • 期号:1
  • 语种:English
  • 出版社:Korean Society of Environmental Health and Toxicology
  • 摘要:Nanotechnology. one of the technologies that forms the core of the recent scienific innovation,is used much in our real lives. Especially products that use nano silver are being sold,with its positive characteristics resulting from the antibacterial effeets of both nano materials and silwer. But critiques have pointed out that nano silver diffused into everyday life too quickly as we do not have done any comprchensive research about the material. and worry that nano silver will afect the ecology adversely. Therefore,this research focuses on investigating the toxicity of silver nanoparticles first. To compare the ffcts of exposure to silver nanoparticles at pre-somite stage and somite stage (10 hours afer frilization),we exposed zebrafsh embryos to silver nanoparicles(15, 30 ppt) during embryogenesis,and then checked the details of eatalase enzyme activity. The hatch rate decreas- ed in the silver nanoparticles exposed groups (15 and 30 pp): furthemore,the hatched fishes had an abnomal notochord,damaged eyes and curved tail. The catialase activities of the 15 pp exposed group at somite stage in- creased relative to those in the control group. Therefore. the silver nanoparticles could seriously damage the de- velopment of zebrafish embryos. Especially. exposure 1o silver nanoparicles at somite stage did severer damage than exposure since pre-somite stage did.
  • 关键词:nanoparticles;silver nano;somite stuge;zebrafish;development
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