出版社：Korean Society of Environmental Health and Toxicology
摘要：Korea Centers for Disease Control and Prevention recently suggested that prolonged inhalation of water aerosol containing biocide in humidifiers can bring about rapidly progressive respiratory fibrosis,which killed more than nine people,including four pregnant women in Korea,based on epidemiologic and toxicological studies [1-4]. It also ordered banning of six consumer products containing three responsible chemicals,oligo [2-(2-ethoxy) ethoxyethyl] guanidium chloride (PGH,AkacidⓇ) and polyhexamethyleneguanidine phosphate (PHMG phosphate,Skybio1125Ⓡ) or hydrochloride (PHMG HCl,Akacid plusⓇ). It suggested that extensive use of a humidifier in a poorly ventilated room with these biocides dissolved in the water could trigger development of fatal pulmonary syndrome,which has never been reported before. Using a humidifier is especially common during the winter season or in households with a respiratory infection patient or a pregnant woman. Biocide for the humidifiers first entered the market at 1994 in Korea and now more than 20 consumer products containing various biocides are available on the market. Considering widespread usage of biocide in humidifiers in this country [5],it is suggested that the total number of the victims by biocide in humidifiers could far exceed the current estimation.
