出版社：Korean Society of Environmental Health and Toxicology
摘要：The effects of ethanol on the toxicity of 2,4-Dichlorophenoxyacetic acid in ICR mice were ex amined. The results were summerized as follows; 1. The LDso of 2.4-dichlorphenoxyacetic acid sodium injected intraperitoneally in mice was approximately 367 mg/kg. When the animals were administered with ethanol, 2 ml/kg or 4 ml/kg the LD3o of 2.4-D sodium were decreased to 338 mg/kg or 32 mg/kg, respectively. 2. In the acute experimental group,spontaneous motor activity in the AN IMEX system exhibited dose-dependent decrease in mice administered with 2.4- D sodium and ethanol. 3. However,in subacute experimental group,spontaneous motor activity in the ANIMEX system exhibited dose-dependent increase in mice treated with ethanol.
