出版社：Korean Society of Environmental Health and Toxicology
摘要：This study was performed to investigate the effect of Angelicae gigantis Radix extract on the hepatic detoxifying enzyme activities and lipids. Male sprague- dawley rats were administrated the extracts with benzo(a)pyrene,a hepatotoxic agent,induc- ing liver damages. Results obtained from this study were as follows: 1. The markedly increased enzyme activities (AST,ALT,LDH,ALP,γ-GTP,GSH -Px) in B(a)P induced groups tended to be decreased by the treatment of the Angelicae gigantis Radix extract. 2. Liver GSH content and lipid peroxide activity were decreased by the administra- tion of the extracts. 3. It tended that the curative effects were better than the protective effects of the extracts.
