出版社:Korean Society of Environmental Health and Toxicology
摘要:The purpose of this study was to characterise the subacute toxic potency of i. v. administered KHPC-005 and 006. Few test compounds-related toxic effects were observed in body weight gain,clinical signs,urinalysis,hematological parameters and serum biochemical values. Gross necropsy and histopathology revealed no evidance specific toxicity. Our data indicated that no-observed effect level of KHPC-005 and 006 were estimated to be 10 mg/kg and 4 mg/kg in male rats,and 10 mg/kg and 1.33 mg/kg in female rats,respectively.