出版社：Korean Society of Environmental Health and Toxicology
摘要：Brazilin was tested for its ability to inhibit alloxan induced lipid peroxidation. Lipid peroxide contents in liver,kidney and serum were measured by the TBA method. ICR mice receiving alloxan at a dose of 43 mgAg via the tail vein after a 24 hrs starvation showed significantly increased lipid peroxide contents as compared to untreated control. Lipid peroxide contents in liver,kidney and serum of alloxan-induced diabetic mice were dose-dependently decreased by the treatment of brazilin at a dose of lOmg/kg,50 mg/kg,100 mg/kg for 5 days.
