出版社：Korean Society of Environmental Health and Toxicology
摘要：Chromatographic retention behavior and separation of various phenol derivatives on a Partisil 10 ODS 3 column-with mobile phase containing 요-cyclodextrin-were systematically studied. The decrease in W values caused by the addition of cyclodextrins in the mobile phase was based on the formation of an inclusion complex,resulting in weakening of the hydrophobic interaction between solutes and the stationary phase. The content of the organic solvent in the mobile phase also influenced k' values of the solutes,and k’ values increased with a decrease of the content of organic solvent in the mobile phase,A simple equation has been derived that reveals the hyperbolic dependence of the capacity factor on the total concentration of cvclodextrin. A plot of the reciprocal of the capacity factor against [CD>r gives a straight line and the dissociation constant. K",of the inclusion complex can be calculated from the slope. The capacity factor decreased with increasing temperature. The enthalpy was calculated from the slope of van’t Hoff plots. Under optimum conditions,some mixtures of phenol derivatives were able to separated successfully.
其他摘要：고성능 액체 크로마토그래피 (high-performance liquid chromatography. HPLC)는 많은 유기 화 함물의 미량분석에,유기 환경 오염 물질의 흡착,분리 및 처리,인체내의 여러 약물 검사 등에 다양 하게 사용되고 있다. M. Arunyanart들은 미셀 이 동상을 이용한 액체 크로마토그래피에서의 선택성 (selectivity)에 대한 연구에서 시료의 머무름에 대 한 미셀 효과吾 설명하기도 했다.1> 2) 丁. Nakagawa 듬
