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  • 标题:The Effect of Tempe Gembus on High-Sensitivity C-Reactive Protein and Adiponectine Levels in Rats with Metabolic Syndrome
  • 本地全文:下载
  • 作者:Ikawati SULISTYANINGSIH ; Diana Nur AFIFAH ; Achmad Zulfa JUNIARTO
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:2020
  • 卷号:66
  • 期号:Supplement
  • 页码:51-55
  • DOI:10.3177/jnsv.66.S51
  • 出版社:Center for Academic Publications Japan
  • 摘要:Metabolic syndrome can affect the inflammatory state which results in increased high-sensitivity C-reactive protein (hs CRP) and decreased adiponectin levels. Tempe gembus is a functional food that can reduce the risk of metabolic syndrome through the inflammatory pathway. This study applied a quasi experimental method, with a post-test only control group design. Sprague Dawley rats ( n =30) were divided into 2 control groups (K− and K ) and 3 treatment groups (P1, P2, P3) which were given a 4-wk diet that included 2.5 g (P1), 5 g (P2), and 7.5 g (P3) of tempe gembus . Adiponectin and hs CRP levels were measured with ELISA. Statistical analysis was done with a one-way ANOVA test and a Kruskal Wallis test. It apprears that administering tempe gembus in these amounts can reduce the hs CRP levels ( p =0.037) and increase adiponectin levels in rats with metabolic syndrome ( p =0.008). This research has shown that a 2.5 g of tempe gembus can have a strong effect on hs CRP and 5 g of tempe gembus have a strong effect on adiponectin.
  • 关键词:metabolic syndrome;tempe gembus;hs CRP;adiponectin
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