摘要：What is already known about this topic? Since 2006, most U.S. mumps cases have been reported among persons who have received 2 doses of measles-mumps-rubella (MMR) vaccine. Mumps is most infectious just before and during the onset of parotitis. What is added by this report? A multistate outbreak followed contact with an asymptomatic, fully vaccinated index patient who reported extensive social interactions at a wedding, resulting in 31 secondary cases, 27 tertiary cases, and three quaternary cases. Isolation and a communitywide third-dose MMR vaccination campaign helped end the outbreak. What are the implications for public health practice? Asymptomatic transmission of mumps in a conducive environment is capable of producing a widespread outbreak. An MMR vaccine campaign can be considered in community settings.
