摘要：What is already known about this topic? Locally acquired cases of Chagas disease are exceedingly rare in the United States. Only 28 autochthonous infections were documented from 1955 to 2015. What is added by this report? In 2017, a blood donation in Missouri screened positive for antibodies to Trypanosoma cruzi , the parasite that causes Chagas disease. Based on the epidemiologic, clinical, and laboratory data, the reported case likely represents the first documented autochthonous case of Chagas disease in Missouri. What are the implication for public health practice? Although most documented cases are among persons originally from Latin America, health care providers and public health professionals should be aware of the possibility of locally acquired Chagas disease in the southern United States.
