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  • 标题:Endoscopic molecular imaging in inflammatory bowel disease
  • 本地全文:下载
  • 作者:Nam Seok Ham ; Seung-Jae Myung
  • 期刊名称:Intestinal Research
  • 印刷版ISSN:1598-9100
  • 电子版ISSN:2288-1956
  • 出版年度:2021
  • 卷号:19
  • 期号:1
  • 页码:33-44
  • DOI:10.5217/ir.2019.09175
  • 出版社:Korean Association for the Study of Intestinal Diseases
  • 摘要:Molecular imaging is a technique for imaging the processes occurring in a living body at a molecular level in real-time, combining molecular cell biology with advanced imaging technologies using molecular probes and fluorescence. Gastrointestinal endoscopic molecular imaging shows great promise for improving the identification of neoplasms, providing characterization for patient stratification and assessing the response to molecular targeted therapy. In inflammatory bowel disease, endoscopic molecular imaging can be used to assess disease severity and predict therapeutic response and prognosis. Endoscopic molecular imaging is also able to visualize dysplasia in the presence of background inflammation. Several preclinical and clinical trials have evaluated endoscopic molecular imaging; however, this area is just beginning to evolve, and many issues have not been solved yet. In the future, it is expected that endoscopic molecular imaging will be of increasing interest among clinicians as a new technology for the identification and evaluation of colorectal neoplasm and colitis-associated cancer.
  • 关键词:Molecular imaging; Intestinal diseases; Inflammatory bowel disease; Colitis; Neoplasm
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