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  • 标题:Dietary Total Antioxidant Capacity and Risk of Non-Alcoholic Fatty Liver Disease: A Case‐Control Study
  • 本地全文:下载
  • 作者:Ammar Salehi-Sahlabadi ; Amin Mokari ; Maryam Elhamkia
  • 期刊名称:Journal of Research in Health Sciences
  • 印刷版ISSN:1682-2765
  • 出版年度:2020
  • 卷号:20
  • 期号:3
  • 页码:1-6
  • DOI:10.34172/jrhs.2020.18
  • 出版社:Hamadan University of Medical Sciences
  • 摘要:BACKGROUND :Dietary total antioxidant capacity (DTAC) has been proposed as a tool for assessing the intake of antioxidants. This study aimed to assess whether a relationship exists between dietary total antioxidant capacity (TAC) and the odds of NAFLD. STUDY DESIGN :A case-control study. METHODS :In this age-and sex-matched case-control study in 2019, patients with NAFLD and healthy controls were recruited from a hospital clinic. All participants completed a validated 168-item food frequency questionnaire, the results of which were subsequently used to generate dietary TAC. Oxygen radical absorbance capacity values were used to calculate dietary TAC. RESULTS :Altogether, 225 patients with NAFLD and 450 healthy controls were enrolled. Participants with NAFLD had a higher mean weight, BMI, energy (P<0.050), and lower physical activity and DTAC scores (P<0.050) than the control group. In an adjusted model, participants who were in the highest quartile of dietary TAC had a lower risk of NAFLD (odds ratio 0.78, 95% CI: 0.67, 0.91). CONCLUSION :A high DTAC was related to a decreased risk of NAFLD. Suggest the intake of a diet with high antioxidant capacity is significant at preventing NAFLD. Increasingly itemized investigations in design of randomized control trials require to reveal more insight into these results.
  • 关键词:Case-control studies;Diet;Non-alcoholic fatty liver disease
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