摘要:The human eye is capable of responding to the presence of blur by changing its axial length, so that the retina moves towards the defocused image plane. We measured how quickly the eye length changed in response to both myopic and hyperopic defocus and how quickly the eye length changed when the defocus was removed. Axial length was measured at baseline and every 10 minutes during 1 hour of exposure to monocular defocus (right eye) with the left eye optimally corrected for two defocus conditions ( 3 D and −3 D) and a control condition. Recovery was measured for 20 minutes after blur removal. A rapid increase in axial length was observed after exposure (~2 minutes) to hyperopic defocus ( 7 ± 5 μm, p < 0.001) while the reduction in axial length with myopic defocus was slower and only statistically significant after 40 minutes (−8 ± 9 μm, p = 0.017). The eye length also recovered toward baseline levels during clear vision more rapidly following hyperopic than myopic defocus (p < 0.0001). These findings provide evidence that the human eye is able to detect and respond to the presence and sign of blur within minutes.