首页    期刊浏览 2024年07月08日 星期一
登录注册

文章基本信息

  • 标题:Combined PLT and NE to predict the prognosis of patients with locally advanced cervical cancer
  • 本地全文:下载
  • 作者:Han Wang ; Wen-Ming Chen ; Yong-Heng Zhou
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2020
  • 卷号:10
  • 期号:1
  • 页码:1-8
  • DOI:10.1038/s41598-020-66387-x
  • 出版社:Springer Nature
  • 摘要:Cervical cancer is one of the most common tumors in women. Neutrophils (NEs) and platelets (PLTs) are components of cells in circulating blood. NEs are one of the components of white blood cells (WBCs), accounting for the vast majority of WBCs, recognized as one of the indicators of inflammation. PLTs are associated with thrombosis and inflammation. Both of them play an important role in tumor growth and metastasis. According to pre-radiotherapy PLT and NE media levels, we divided the patients into three groups: PLT and NE both high levels group, single high level group and both low group. By using COX regression models and nomogram, a prognostic model for patients was established. Both high levels of pre-radiotherapy PLT and NE group or high levels of post-radiotherapy PLT and NE group were correlated with worst overall survival (OS) compared with the other two groups. PLT and NE were correlated with outcomes of the patients with locally advanced cervical cancer.
国家哲学社会科学文献中心版权所有