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  • 标题:Epidemiological analysis of asymptomatic SARS-CoV-2 transmission in the community: an individual-based model
  • 本地全文:下载
  • 作者:Zuiyuan Guo ; Dan Xiao
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2021
  • 卷号:11
  • 期号:1
  • 页码:6251
  • DOI:10.1038/s41598-021-84893-4
  • 出版社:Springer Nature
  • 摘要:Abstract We established an individual-based computer model to simulate the occurrence, infection, discovery, quarantine, and quarantine release (recovery) of asymptomatic SARS-CoV-2 infected individuals or patients within the community. The model was used to explore the effects of control measures, such as active tracing, laboratory testing, active treatment, and home quarantine on the epidemic. Considering the condition that R 0  = 1.2, when a case of an imported asymptomatic infected individual (AII) was reported in the community, the implementation of control measures reduced the number of AIIs and patients by 62.2% and 62.4%, respectively. The number of undetected AIIs and patients peaked at 302 days of the epidemic, reaching 53 and 20 individuals, respectively. The implementation of sustained active tracing, laboratory testing, active treatment, and home quarantine can significantly reduce the probability of disease outbreaks and block the spread of the COVID-19 epidemic caused by AIIs in the community.
  • 其他摘要:Abstract We established an individual-based computer model to simulate the occurrence, infection, discovery, quarantine, and quarantine release (recovery) of asymptomatic SARS-CoV-2 infected individuals or patients within the community. The model was used to explore the effects of control measures, such as active tracing, laboratory testing, active treatment, and home quarantine on the epidemic. Considering the condition that R 0  = 1.2, when a case of an imported asymptomatic infected individual (AII) was reported in the community, the implementation of control measures reduced the number of AIIs and patients by 62.2% and 62.4%, respectively. The number of undetected AIIs and patients peaked at 302 days of the epidemic, reaching 53 and 20 individuals, respectively. The implementation of sustained active tracing, laboratory testing, active treatment, and home quarantine can significantly reduce the probability of disease outbreaks and block the spread of the COVID-19 epidemic caused by AIIs in the community.
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