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标题：Effects of sleep-inducing juice on sleep quality and heart rate variability in adults with disturbed sleep
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作者：Choun-sub Kim ; Maengkyu Kim ; Min-ju Kim 等
期刊名称：Nutrition Research and Practice
印刷版ISSN：1976-1457
出版年度：2020
卷号：14
期号：6
页码：606-620
DOI：10.4162/nrp.2020.14.6.606
出版社：KoreaMed Synapse
摘要：BACKGROUND/OBJECTIVES :Although some juices affect subjective sleep quality, there is a lack of information on the effect of a specific juice on objective sleep quality and heart rate variability (HRV) during sleep; thus the present study investigated whether a blended juice made from natural extracts influenced sleep quality and HRV during sleep in adults with disturbed sleep. SUBJECTS/METHODS :A randomized, crossover study was conducted on twenty-five adults (15/10, female/male) complaining of difficulty initiating or maintaining nighttime sleep (Pittsburgh sleep quality index [PSQI] ≥ 5). During feeding sessions (FS), subjects received sleep-inducing juice made of natural ingredients (250 mL/trial) twice a day for 8 weeks or non-FS (N-FS) for 8 weeks while maintaining normal activities. Sleep quality and parameters were recorded via wearable actigraph for 7 consecutive days, and PSQI scores were assessed before and after the intervention. HRV was also monitored at rest and during sleep. RESULTS :After receiving the sleep-inducing juice intervention (FS), PSQI scores were significantly decreased ( P < 0.001) and correlated with a significant decline in fatigue severity scale and visual analogue scale levels ( P < 0.05; both). HRV indices of vagal activity were significantly improved during FS ( P < 0.05), and no significant differences in N-FS were observed. Sleep efficiency and total sleep time increased significantly ( P < 0.05) and sleep latency, total counts, sleep fragmentation index, and movement index, decreased significantly ( P < 0.05, all 4) during FS, with no significant differences-observed during N-FS. CONCLUSIONS :This study results demonstrated that an 8-week course of sleep-inducing juice has led to improve sleep quality, suggesting an enhanced cardiac vagal tone during sleep. Thus, it could be a well-tolerated option for adults with disturbed sleep. ©2020 The Korean Nutrition Society and the Korean Society of Community Nutrition.
关键词：Cross-over studies;autonomic nerves;heart rate;sleep latency