文章基本信息

标题：Potential use of 3-(trimethoxysilyl)propyldimethyl octadecyl ammonium chloride as an antimicrobial and antiviral agent for the disinfection of personal protective equipment
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作者：Yujin Kim ; Hana Youn ; Junbeom Kim 等
期刊名称：Clinical and Experimental Vaccine Research
印刷版ISSN：2287-3651
出版年度：2020
卷号：9
期号：2
页码：174-178
DOI：10.7774/cevr.2020.9.2.174
出版社：KoreaMed Synapse
摘要：Currently, no vaccine or established therapeutic agents are available for coronavirus disease 2019. The sharp increase in demand for personal protective equipment (PPE) necessitates an improvement in the protective efficacy of PPE. We evaluated the potential antimicrobial and antiviral effects of a surface-coating disinfectant (3-(trimethoxysilyl)propyldimethyl octadecyl ammonium chloride, Si-QAC) when applied onto PPE. Si-QAC-pre-coated PPE was artificially contaminated with either influenza virus or Salmonella . The results showed significantly reduced influenza and Salmonella titers in Si-QAC-coated PPE; these antimicrobial effects lasted 7 days. This suggests that this surface-coating disinfectant effectively reduces pathogen contamination of PPE, enabling their safe and long-term use. © Korean Vaccine Society.
关键词：Antimicrobial;Antiviral;Coating disinfectant;Long-lasting;Si-QAC