标题：The Estimated Prevalence and Incidence of Endometriosis With the Korean National Health Insurance Service-National Sample Cohort (NHIS-NSC): A National Population-Based Study
摘要：BackgroundThe incidence and prevalence of endometriosis remain unclear due to diagnostic difficulties. Especially, there has been little information regarding the population-based epidemiology of endometriosis. The purpose of this study is to estimate the prevalence and incidence of endometriosis in Korea based on the health insurance claims data.MethodsThis study is a retrospective cohort study using the Korean National Health Insurance Service-National Sample Cohort, which correspond to approximately 1 million Korean populations from 2002 to 2013. Patients aged 15-54 were selected, and the prevalence and incidence of endometriosis were estimated by time and age groups.ResultsThe age-adjusted prevalence rate of endometriosis also increased from 2.12 per 1000 persons (95% confidence interval [CI], 2.01-2.24) in 2002 to 3.56 per 1000 persons (95% CI, 3.40-3.71) in 2013. The average adjusted incidence showed no statistically significant increase. However, the age-specific incidence of the age group 15-19 and 20-24 increased significantly from 0.24 and 1.29 per 1000 persons in 2003 to 2.73 and 2.71 per 1000 persons in 2013 (R 2 =0.93 and 0.77, P <0.001), while the incidence rate of the age group 40-44 and 45-49 decreased from 2.36 and 1.72 per 1000 persons in 2003 to 0.81 and 0.27 per 1000 persons in 2013 (R 2 =0.83 and 0.89, P <0.001).ConclusionThe prevalence and incidence of endometriosis in Korean women were lower than that of previous reports in high-risk population studies. Furthermore, we found a significant increase in the diagnosis of endometriosis in younger age groups.
