摘要:Regular physical activity as a non-pharmacological intervention to increase bone strength, bone density and fracture prevention is recommended. The aim of this study was to evaluate the effect of eight weeks’ endurance training on biomechanical and geometrically parameters of the femur and tibia bones in male Wistar rats. 16 rats with an age range of 50 to 60 days and an average weight of 160 ± 10 gr, were randomly divided into two groups: eight weeks of endurance training (running five days a week, according to the training protocol) and control group (no activity). After the end of the training, the rats were sacrificed, the right femur and tibia bones were harvested, then By mechanical three-point bending test, the biomechanical parameters (stiffness, maximum mechanical strength and maximum energy to the point of maximum strength) and by digital caliper, geometric parameters (length and width) were measured. One way-ANOVA was used to compare biomechanical and geometrical parameters between groups. The results demonstrated a significant increase in biomechanical parameters (stiffness, maximum mechanical strength and maximum energy to the point of maximum strength) and geometrical parameters (length and width) of the femur and tibia (except length) bones after eight weeks’ endurance training. Eight weeks’ endurance training (used in this study) improved the biomechanical and geometrical parameters of the femur and tibia bones.