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  • 标题:Mental adjustment to cancer and survival of patients admitted for allogenic hemopoietic stem cell transplantation
  • 本地全文:下载
  • 作者:Norbert Grulke ; Harald Bailer ; Wolfgang Larbig
  • 期刊名称:GMS Psycho-Social-Medicine
  • 印刷版ISSN:1860-5214
  • 出版年度:2006
  • 卷号:3
  • 页码:1-9
  • 出版社:German Medical Science
  • 摘要:Objective: The Mental Adjustment to Cancer Scale (MAC scale) has evolved to a standard measure in the field of psycho-oncology. In this context an attitude called "fighting spirit" gained much attention as a coping style. Some reports suggest that coping efforts as measured by the MAC scale are predictive for survival of breast cancer patients. We explored the predictive power of the MAC scale by using a sample of patients with haematological malignancies undergoing allogenic hemopoietic stem cell transplantation (HSCT). Methods: Between 9/1999 and 12/2001 127 patients were administered the MAC scale prior to HSCT. Follow-up data of overall survival and event-free survival were obtained in December 2003 and analyzed using Cox-regression models. Results: At the time of the follow-up, 68 patients had died (overall survival), 75 patients had experienced a relapse or had died (event-free survival). We failed to find significant results for the MAC subscales with and without adjustment for prognostic factors. Conclusion: In the special situation of patients facing HSCT the MAC scale seems not to be of predictive value. In general, with respect to survival the empirical evidence is not very convincing.
  • 关键词:survival; psychological response; coping; neoplasm; stem cell transplantation
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