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  • 标题:credsubs: Multiplicity-Adjusted Subset Identification
  • 本地全文:下载
  • 作者:Patrick M. Schnell ; Mark Fiecas ; Bradley P. Carlin
  • 期刊名称:Journal of Statistical Software
  • 印刷版ISSN:1548-7660
  • 电子版ISSN:1548-7660
  • 出版年度:2020
  • 卷号:94
  • 期号:1
  • 页码:1-22
  • DOI:10.18637/jss.v094.i07
  • 出版社:University of California, Los Angeles
  • 摘要:Subset identification methods are used to select the subset of a covariate space over which the conditional distribution of a response has certain properties - for example, identifying types of patients whose conditional treatment effect is positive. An often critical requirement of subset identification methods is multiplicity control, by which the family-wise Type I error rate is controlled, rather than the Type I error rate of each covariate-determined hypothesis separately. The credible subset (or credible subgroup) method provides a multiplicity-controlled estimate of the target subset in the form of two bounding subsets: one which entirely contains the target subset, and one which is entirely contained by it. We introduce a new R package, credsubs, which constructs credible subset estimates using a sample from the joint posterior distribution of any regression model, a description of the covariate space, and a function mapping the parameters and covariates to the subset criterion. We demonstrate parametric and nonparametric applications of the package to a clinical trial dataset and a neuroimaging dataset, respectively.
  • 关键词:credible subgroups;multiple hypothesis testing;R;subset identification;subgroup analysis.
  • 其他关键词:credible subgroups;multiple hypothesis testing;R;subset identification;subgroup analysis
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