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  • 标题:Aflatoxin exposure among lactating women in southern Ethiopia
  • 本地全文:下载
  • 作者:Bergene Boshe ; Samson Gebremedhin ; Fikadu Alemayehu
  • 期刊名称:Food Science & Nutrition
  • 电子版ISSN:2048-7177
  • 出版年度:2020
  • 卷号:8
  • 期号:12
  • 页码:6738-6745
  • DOI:10.1002/fsn3.1968
  • 出版社:John Wiley & Sons, Ltd.
  • 摘要:In Ethiopia and many other low‐income countries, little is known about the exposure of lactating women to aflatoxin, which is a major health concern to the mother and her nursing infant. We determined the aflatoxin B 1 contamination of family foods (AFB 1 ) and urinary aflatoxin M 1 (AFM 1 ) of lactating women in Sidama, southern Ethiopia, and compared the levels across agroecological settings (lowland, midland, highland) and two seasons. We conducted two surveys ( n = 360) that represented the dry and wet seasons of the locality. AFM 1 and AFB 1 were determined using enzyme‐linked immunosorbent assay (ELISA). Statistical analysis was made using Mann–Whitney U test and Kruskal–Wallis test. The median (interquartile range) AFB 1 was 0.94 (0.63–1.58) ppb. AFB 1 was detected in 95.6% of the food samples, and 13.6% exceeded the 2.0 ppb threshold. We observed an increasing trend for aflatoxin exposure from highland to lowland ( p < .001), but there was no difference between seasons ( p = .743). The median (interquartile range) urinary AFM 1 was 214 (undetectable to 2,582) ppt, and AFM 1 was detectable in 53.3% of the samples. Urinary AFM 1  showed significant difference among agroecological zones ( p < .001) but not between seasons ( p = .275). A significant but weak correlation was observed between AFB 1 and urinary AFM 1 ( r s = 0.177, p = .001). We concluded that lactating women in Sidama, especially those in the lowland area, have unsafe exposure to aflatoxin.
  • 关键词:Aflatoxin B1;agroecology;food;lactating women;seasonality;urinary aflatoxin M1
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