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  • 标题:Bisphenols and the Development of Type 2 Diabetes: The Role of the Skeletal Muscle and Adipose Tissue
  • 本地全文:下载
  • 作者:Fozia Ahmed ; Maria João Pereira ; Céline Aguer
  • 期刊名称:Environments
  • 电子版ISSN:2076-3298
  • 出版年度:2021
  • 卷号:8
  • 期号:4
  • 页码:35
  • DOI:10.3390/environments8040035
  • 出版社:MDPI Publishing
  • 摘要:Bisphenol A (BPA) and bisphenol S (BPS) are environmental contaminants that have been associated with the development of insulin resistance and type 2 diabetes (T2D). Two organs that are often implicated in the development of insulin resistance are the skeletal muscle and the adipose tissue, however, seldom studies have investigated the effects of bisphenols on their metabolism. In this review we discuss metabolic perturbations that occur in both the skeletal muscle and adipose tissue affected with insulin resistance, and how exposure to BPA or BPS has been linked to these changes. Furthermore, we highlight the possible effects of BPA on the cross-talk between the skeletal muscle and adipose tissue.
  • 关键词:BPA; BPS; skeletal muscle; adipose tissue; insulin resistance; type 2 diabetes BPA ; BPS ; skeletal muscle ; adipose tissue ; insulin resistance ; type 2 diabetes
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