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  • 标题:Bacterial extracellular matrix as a natural source of biotechnologically multivalent materials
  • 本地全文:下载
  • 作者:Carlos Molina-Santiago ; Antonio de Vicente ; Diego Romero
  • 期刊名称:Computational and Structural Biotechnology Journal
  • 印刷版ISSN:2001-0370
  • 出版年度:2021
  • 卷号:19
  • 页码:2796-2805
  • DOI:10.1016/j.csbj.2021.05.008
  • 出版社:Computational and Structural Biotechnology Journal
  • 摘要:The extracellular matrix (ECM) is an intricate megastructure made by bacterial cells to form architecturally complex biostructures called biofilms. Protection of cells, modulation of cell-to-cell signalling, cell differentiation and environmental sensing are functions of the ECM that reflect its diverse chemical composition. Proteins, polysaccharides and eDNA have specific functionalities while cooperatively interacting to sustain the architecture and biological relevance of the ECM. The accumulated evidence on the chemical heterogeneity and specific functionalities of ECM components has attracted attention because of their potential biotechnological applications, from agriculture to the water and food industries. This review compiles information on the most relevant bacterial ECM components, the biophysical and chemical features responsible for their biological roles, and their potential to be further translated into biotechnological applications.
  • 关键词:Bacterial biofilms ; Extracellular matrix ; Amyloid proteins ; Exopolysaccharides ; Biotechnological applications
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