标题：Role of biochemical parameters in the differential diagnosis of viable pregnancy, anembryonic pregnancy and intrauterine fetal exitus in cases of first trimester threatened abortion
摘要：It is aimed to establish criteria about the prognosis and life potential of pregnancy by using ultrasonographic imaging techniques and hormonal parameters to evaluate embryonic life potantial in threatened miscarriage patients. Our study consists of 45 pregnant patients who were admitted for vaginal bleeding during pregnancy and were diagnosed as a threatened miscarriage. The study group consisted of pregnant women diagnosed with threat of miscarriage pregnancy week is lower than 20 weeks according to their last menstrual period. Estradiol, Progestrone, β-hCG hormone level are measured from patients, the same day after the ultrasound examination. The group whose pregnancy resulted with live birth and the group whose pregnancy ended with spontaneous abortion were statistically compared according to their hormonal parameters; it was found to be significantly lower in the group that resulted in live birth (p <0.01). Sensitivity, specificity, negative and positive predictive values of β-hCG, E2, P4 levels were found to be significant in patients with threatened miscarriage. Increase both time loss and correct diagnosis rate, after vaginal speculum examination the first choice in patients with abortus imminens is to request a transvaginal ultrasonographic examination and then assesment of hormonal parameters (β-hCG, progesterone, estradiol) if necessary.
