摘要：To evaluate the role of microalbuminuria at admission as a prognostic marker in comparison to standard mortality scores-Paediatric Risk of Mortality (PRISM) and Paediatric Logistic Organ Dysfunction (PELOD) in children admitted to Paediatric Intensive Care Unit (PICU). This Cross-sectional study was conducted from January 2015 to October 2016. Eighty-four patients, of the age one month to eighteen years admitted to PICU of teaching hospitals for more than 24 hours were enrolled by convenient sampling method. Microalbuminuria was estimated by spot urinary albumin-creatinine ratio (ACR) . PRISM and PELOD scores were calculated using an online calculator. Outcome measures were the length of stay in PICU, inotrope usage, the presence of multiorgan dysfunction and survival. Albumin-creatinine ratio was compared with mortality scores for prediction of survival. Microalbuminuria was present in 79.8% with median value of 85mg/g[Inter Quartile range(IQR),41.5-254].Positive correlation was found between albumin -creatinine ratio and PICU stay(p=0.013, r=0.271). Albumin- creatinine ratio had significant association with organ dysfunction (p=0.004) and need of inotropes (p=0.006).Eight deaths were observed in PICU. The area under the curve (AUC) for mortality for ACR (0.822) was comparable to PRISM (0.928) and PELOD (0.877). The value of albumin - creatinine ratio >109mg/g predicted mortality with the sensitivity of 87.5% and specificity of 63.2%. Microalbuminuria is a good predictor of outcome in PICU and is comparable with Mortality scores.
