摘要：The antioxidant actions of 80% ethanolic extract of dried flowers of Hibiscus sabdariffa L. (HSE) on lipid peroxidation (LPO), reduced glutathione (GSH), glutathione-s-transferase (GST), catalase (CAT), superoxide dismutase (SOD) and vitamin C (VITC), were examined using a model of sodium arsenite (SA) - induced oxidative stress in rats. The oral administration of the extracts (200 and 300mg/kg body weight) significantly (P in vitro ) by their capacity of quenching 1, 1-diphenyl - 2-picrylhydraxyl (DPPH) free radical , showed strong scavenging effects on DPPH free radical at concentration of 0.20mg/ml (1C50 = 0.20mg/ml). The extracts at low and high concentrations showed no inhibitory effect on nitric oxide radical. These findings are suggestive of the possible chemopreventive and antioxidative role played by dried flower extract of Hibiscus sabdariffa L.
