摘要：A study on the effect of low- protein diet on the toxicity of acute doses of Actellic-20 in the heart and brain of albino rats was carried out. Three weeks old weaning albino rats Rattus norvegicus were grouped into two and fed low and normal protein diet for four weeks after which they were given Actellic-20 at low dose levels (100ppm and 150ppm) by oral intubation. The rats were sacrificed at 24h, 72h, and 120h after dosing and the activities of Alkaline phosphatase, Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) were monitored in these tissues. The activities of Alkaline phosphatase, Alanine aminotransferase and Aspartate aminotransferase were significantly reduced (P amino acid metabolism in these organs.
