摘要：The purpose of the present study was to evaluate the effect of oral cadmium exposure on the activities of ocular superoxide dismutase , catalase, ATPases and level of lipid peroxidation using the rat as animal model. Forty male albino rats (Wistar strain) were divided into four groups of ten animals each; one group received de-ionized water and acted as control. The other groups, which were the tests, received 50, 100 and 200 mg Cd L-1, respectively in drinking water for one month. The results obtained indicate a significantly (p superoxide dismutase activity and a corresponding increase in level of lipid peroxidation of cadmium exposed rats as compared to control. No significant (p>0.05) change was observed in the activities of catalase and Mg2+ ATPase, but a dose dependent increase in the activities of total and Na+/K+ ATPase were observed in the eyes of rats orally exposed to cadmium as compared to control. The study suggests that exposure to cadmium enhanced oxidative stress and Na+/K+ ATPase activity in the eyes of rats.
