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文章基本信息

  • 标题:Convenient Approach to Access Octa-Glycosylated Porphyrins via “Click Chemistry”
  • 本地全文:下载
  • 作者:Misako Okada ; Yuko Kishibe ; Kanako Ide
  • 期刊名称:International Journal of Biomedical Imaging
  • 印刷版ISSN:1687-4188
  • 电子版ISSN:1687-4196
  • 出版年度:2006
  • 卷号:2006
  • DOI:10.1155/2009/305276
  • 出版社:Hindawi Publishing Corporation
  • 摘要:

    Easy, quantitative, and one-pot introduction of eight β -lactoside-modules onto a porphyrin-core was achieved through Cu + -catalyzed chemoselective coupling (click chemistry) between a porphyrin carrying eight alkyne-terminals and β -lactosyl azides. The obtained porphyrin-based glycocluster shows not only good water-solubility but also strong/specific lectin-affinity.

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