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  • 标题:Development of a new disinfectant with very strong anti-influenza viral activity: a preliminary report
  • 本地全文:下载
  • 作者:Hiroki Takakuwa ; Toshiyuki Maruoka ; Tadayo Hata
  • 期刊名称:Environmental Health and Preventive Medicine
  • 印刷版ISSN:1342-078X
  • 电子版ISSN:1347-4715
  • 出版年度:2010
  • 卷号:15
  • 期号:2
  • 页码:121-123
  • DOI:10.1007/s12199-009-0112-y
  • 语种:English
  • 出版社:Springer Japan
  • 摘要:Objectives

    We evaluated the effectiveness and safety of a disinfectant newly developed by our laboratories for use against influenza viruses.

    Methods

    The effectiveness of our new disinfectant against avian, swine and human influenza viruses was tested in ovo. The acute toxicity of this disinfectant to two different cultured cell lines was investigated.

    Results

    This new disinfectant showed very strong anti-influenza viral activity in the in ovo tests. All of the influenza viruses tested were inactivated very quickly. Following exposure to the disinfectant, the infectivity of all viral strains tested had been eliminated within ≤10 min. The infectant showed a weak acute toxicity in vitro.

    Conclusion

    This new disinfectant is expected to be useful for preventing viral infection during a new influenza pandemic.

  • 关键词:Avian influenza virus ;Human influenza virus ;New disinfectant ;Strong activity ;Swine influenza virus
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