The processing of the huge amounts of information in the bioinformatics has been the bottleneck to restrict its development, and in this article, we used the distributed computation to solve this problem, and we described the structure, the design, the implementation of task decomposition, the distributed application program and the database management of the distributed computing platform. The distributed computing platform first decomposes one problem into many subtasks, and then the client sends the request of task computation for the server end, and the server end responses the request and takes out the information of the minimum subtask, and distribute the information to the client end. When the client end acquires the information of the subtask, it will transfer the operation module to compute, and when the task is completed, it will upload the result to the server end, and the server end repeats above process until all subtasks are completed, and according to the computation results of all subtasks, we can obtain the solution of the problem.