In this paper, according to the fieldwork and statistic analysis, the issues for the relativity between airborne microbes and environmental factors in Pearl River delta’ Urban Agglomeration, Guangdong are discussed using ecological method in order to research on health prevention and environment control measures in Pearl River delta’ Urban.

The results show that as follow: (1) T he average content of airborne microbes (fungi and bacteria) in Guangzhou and Dongguan is higher than other 6 cities in Pearl River delta’ Urban; the content of bacteria is higher than fungi; outdoor content is higher than indoor content; the average content of airborne microbe in the area without greenbelt is higher than the area with greenbelt; the average content of airborne microbe are higher during spring and summer than other seasons.

(2) T here are obvious relativity between the average content of airborne microbes (fungi and bacteria) and environment factors (wind speed, humidity, temperature, total suspended particulate (Tsp); Furthermore, most of those have positive or negative linear relationship.

(3) T here are also obvious relativity between the average content of airborne microbes (fungi and bacteria) and the number of person flowrate, car flowrate and condition of afforestation , population density.